7 Best Lions Mane Supplements

By Amber Smith; Medically Reviewed by Diana Rangaves, PharmD, RPH
Jan 9, 2024 5:00 AMJan 11, 2024 6:49 PM
Elm and Rye


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Reviewed by Dr. Diana Rangaves, PharmD, Clinical Consultant Services, Google Scholar 

This mushroom, the lions mane, has been used in Eastern medicine for centuries but has recently become wildly popular in the Western world. Lions mane is known for many things like improved focus, but most recently has shown promise in stimulating neural nerve growth

Not only that, but we’ve learned that lions name can help improve your immune system while reducing inflammation. These are two important factors right now with chronic inflammation becoming a topic that many are coping with and discussing. With all that being said, there are so many dietary supplements these days that feature lions mane, so today we wanted to give you a list of the 7 best lions mane supplements to select from. 

7 Best Lions Mane Supplements

What are lions mane supplements? 

Lions mane mushrooms look like white shaggy mushrooms, but when used in a supplement form you won’t see them in their original form, obviously. The lions mane supplements featured on our list include an extract of the mushroom alongside other important vitamins and herbs to help you with wellness. 

These mushrooms are most commonly used to improve focus, memory, and brain clarity. We’ve seen many studies reference these mushrooms for improved cognitive function. 

Elm & Rye Mushroom Complex

Mushrooms like the reishi, chaga, cordyceps, lions mane, and turkey tail have become wildly popular even though they’ve been used in traditional Chinese medicine for thousands of years. These mushrooms promote better wellness and health.

Elm & Rye Mushroom Complex is here to help you get your daily dose of mushrooms for maximum health and wellness this New Year. They’ve been crafted to be the best of the best lions mane supplements for people to consume. This blend is available in capsules, gummies, or coffee creamer to satisfy each person’s taste. 

BATCH Brain Boost Mushroom Gummies

These chews are an excellent option for anyone looking to use lions mane supplements in a candy form. These chewable gummies from BATCH are made with a wild berry flavor to ensure you enjoy the lions mane, reishi, and cordyceps mushrooms aren’t tasted when you consume this supplement. 

Each package of BATCH brain boost mushroom gummies comes in a 30-pack container to help support your nervous system all month long. 

Perpetua Life Li

These gummies are an easy way to get the benefits of lions mane mushrooms. This supplement blends 10 different mushrooms to get your daily fix with ease. The brand prides itself on getting all 10 mushrooms into 1 supplement so you don’t have to take multiple gummies or supplements to harness the power of mushrooms.  

Stonehenge Health 

These mushrooms are a dietary supplement formulated to put various mushrooms into one capsule, much like the referenced option above. This one has reishi, chaga, lions mane, and turkey tail to provide the most advanced nourishment for your immune system. 

With each serving of this supplement, you’ll be well on your way to improved immunity, strength, and mental clarity. 

Wild Foods Co 

Wild Foods Co features a tasty option for those looking for lions mane supplements in capsule form. This supplement is made with 100% USDA-certified organic mushrooms and is easy to consume for busy men and women seeking mental vitality. With just two capsules daily, you get to enjoy improved health and wellness with ease. 

Fresh Cap 

Fresh Cap features a capsule or powder form option for those who want to mix up their lions mane supplements into coffee or another beverage. Each mushroom complex supplement from Fresh Cap features a blend to improve mood, brain clarity, and focus

Chaos and Pain MUSH-TEN 

This 10-in-1 mushroom complex is a dietary supplement formulated with reishi, chaga, lions mane, turkey tail, and cordyceps. These mushrooms may help strengthen your immune system while improving clarity and brain function like lions mane does

Our Criteria For The 7 Best Lions Mane Supplements 

  • Ingredients & Quality: One of the key factors to selecting the top 7 lions mane supplements was ingredients & quality. These ingredients needed to be of the utmost quality, including organic whenever possible. 

  • Safety Considerations:  Next in our criteria for choosing these lions mane supplements are safety considerations. We wanted to make sure that the ingredients are science-backed, meaning that studies promote the use of the various ingredients in dietary supplements for use in humans. Even though the ingredients are safe, please be sure to consult a physical for the safety of the lions mane supplement with any medications you may be on currently. 

  • Customer Reviews: Not only were the above two factors important, but customer reviews were imperative, too! We read through hundreds of customer reviews to sift and sort which of the lions mane supplements online were suitable for our list today. 

  • Flavor Options: The final option we reviewed for lions mane supplements was the flavor profile. Some of the 7 best lions mane supplements have a fruit flavor added while others have no flavor profile. 


Are lions mane mushrooms supplements good?

Yes, these supplements are good. Most of the capsules, powders, and gummies are either flavored or unflavored so you can enjoy the health benefits of mushrooms without tasting the Earthy flavor of mushrooms

Do lions mane mushroom supplements work? 

We’ve seen studies that reference lions mane mushrooms work well, even when in a placebo-based comparison study. Each participant scored higher on cognitive tests after taking lions mane mushroom supplements compared to those who took a placebo. 

Is lions mane mushrooms extract safe? 

Yes, lions mane mushroom supplements that contain lions mane mushrooms extract are safe. These supplements have been formulated to be safe for human consumption based on science-back evidence for vitamins, herbs, and other natural ingredients; including often organic mushrooms. 

Where to buy lions mane mushroom supplement?

You can purchase lions mane supplements online or at a local Whole Foods store. We’ve featured the best lions mane supplements to help you easily deliver them to your doorstep. This is a convenient option for anyone living in rural areas or not wanting to leave the house to go shopping. 

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