The Evolutionary Quirk That Made Vitamin B12 Part of Our Diet

If animal products are our only source of B12, and it's vital to survival, how do herbivores survive?

The Crux
By Nathan H. Lents
Aug 13, 2018 7:15 PMOct 4, 2023 8:00 PM
Vitamin B12 foods - Shutterstock
(Credit: bitt24/Shutterstock)

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Vitamins and other nutrients that we cannot make for ourselves are called essential. It’s a misleading term because “essential” most often means “important,” but in the world of dietetics, it denotes that we must obtain it in our diets. For example, vitamin Q, also called ubiquinone, is extremely important — it’s crucial for cellular respiration in the mitochondria — but it is not deemed essential because our cells simply make this biomolecule from already available parts.

Humans have a very needy diet when it comes to essential micronutrients, more so than other animals. This likely stems from an evolutionary past in which our ancestors enjoyed a richly varied diet and obtaining vitamins and minerals was rarely a challenge. As I’ve written previously, we need vitamin C in our diet, whereas most animals don’t, because a distant ancestor already had abundant vitamin C in her diet when she suffered the mutation that killed one of the genes for vitamin C synthesis. The story of vitamin D deficiency is another example of wonky evolution in our lineage that you can read about here.

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